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Table 1 Intervention lists

From: Drugs commonly associated with weight change: umbrella systematic review and meta-analysis (Protocol)

List A (Leptogenic)

List B (Obesogenic)

Drug classes

Drug classes

1.

ACE inhibitors

1.

Insulin I.M or S.C.

2.

Calcium channel blockers

2.

Oral nasal decongestants

3.

MAOIs

3.

Protease inhibitors

4.

NSAIDs

4.

Sulfonylureas

5.

Oral antihistamines

5.

Oral hormonal contraceptives containing progestational steroids

6.

Oral corticosteroids

  

Specific drugs a

Specific drugs a

1.

Acarbose

1.

Amitriptyline

2.

Aripiprazole

2.

Atenolol

3.

Bromocriptine

3.

Carbamazepine

4.

Bupropion

4.

Citalopram

5.

Bupropion + Naltrexone

5.

Clozapine

6.

Cabergoline

6.

Doxazosin mesylate

7.

Duloxetine

7.

Doxepin

8.

Exenatide

8.

Escitalopram

9.

Fluoxetineb

9.

Fluvoxamine

10.

Growth hormone I.V or S.C.

10.

Gabapentin

11.

Lamotrigine

11.

Gamma - hydroxybutyric acid

12.

Liraglutide

12.

Leuprolide

13.

Metformin

13.

Lithium

14.

Miglitol

14.

Metoprolol

15.

Nefazodone

15.

Mirtazapine

16.

Octreotide

16.

Nateglinide

17.

Orlistat

17.

Nortriptyline

18.

Phentermine resin diethylpropion

18.

Olanzapine

19.

Pramlintide

19.

Paroxetine

20.

Sertralineb

20.

Pioglitazone

21.

Sitagliptin

21.

Propranolol

22.

Testosterone

22.

Quetiapine

23.

Topiramate

23.

Repaglinide

24.

Topiramate + Phentermine

24.

Risperidone

25.

Ziprasidone

25.

Terazosin

26.

Zonisamide

26.

Valproate

  

27.

Venlafaxine

  1. aAll of these drugs do not fall into the listed classes.
  2. bThese drugs show a bimodal behavior, may cause weight loss in the first year and weight gain in the second year of use.