Outcome: Headache persistence | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | GRADE factors | ||||||||||||||||
Potential prognostic factors identified | Number of participants | Number of studies | Number of cohorts | + | 0 | - | + | 0 | - | Phase | Study limitations | Inconsistency | Indirectness | Imprecision | Publication bias | Moderate/large effect size | Dose effect | Overall quality |
Headache intensity | 536 | 3 | 1 | 2 | 0 | 1 | ✕ | ✓ | ✓ | ✓ | ✕ | ✕ | ✕ | + | ||||
Age | 867 | 3 | 1 | 2 | 0 | 1 | ✕ | ✕ | ✓ | ✓ | ✕ | ✕ | ✕ | + | ||||
Type of headache diagnosis | 249 | 3 | 2 | 1 | 0 | 1 | ✕ | ✓ | ✕ | ✓ | ✕ | ✓ | ✕ | + | ||||
Menstruation | 449 | 1 [22] | 1 | 0 | 1 | 0 | 1 | ✕ | ✕ | ✕ | Unclear | ✕ | ✕ | ✕ | + | |||
Sex | 3,272 | 4 | 1 | 2 | 0 | 1 | 3 | 0 | 1 | ✕ | ✓ | ✓ | ✓ | ✓ | ✓ | ✕ | +++ | |
Family history of pain | 654 | 2 | 2 | 0 | 0 | 1 | 1 | 0 | 1 | ✓ | ✕ | ✕ | ✓ | ✕ | ✓ | ✕ | + |