Parameters | Description |
---|---|
Type of studies | All randomised controlled trials of mild hypothermia versus control (open or normothermia) will be included |
Types of participants | Patients with any closed head injury requiring hospitalisation |
Types of interventions | Therapeutic cooling, either locally or systemically, by means of a fluid-filled cooling blanket, a ‘bear-hugger’ air-cooling device, ice water lavage, any combination of the above, or other methods, to a target temperature of at most 34–35 degrees Celsius for a period of at least 12 h |