From: Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol
Population | • adult patients with traumatic brain injury |
Intervention | • red blood cell transfusion |
Comparator | • no transfusion |
Primary outcome | • frequency of red blood cell transfusion |
Secondary outcomes | • transfusion thresholds |
• number of red blood cell units transfused | |
• determinants of red blood cell transfusion | |
• mortality | |
• frequency of withdrawal of life-sustaining therapy | |
• frequency of unfavourable neurological outcome | |
• ICU and hospital length of stay | |
• all other reported clinical outcomes | |
Study design | • cohort studies (both prospective and retrospective) and randomized controlled trials |