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Table 1 PECOD question for the systematic review

From: The effect of hormone therapy on all-cause and cardiovascular mortality in women with chronic kidney disease: protocol for a systematic review and meta-analysis

Population

Women with chronic kidney disease (as defined by eGFR or presence of kidney damage)

Population

Women with chronic kidney disease (as defined by eGFR or presence of kidney damage)

Exposure

Hormone Therapy (HT) (all types of HT including estradiol alone or estradiol and progesterone)

Comparator

Placebo or No HT

Outcome

All-cause and cardiovascular mortality

Design

RCTs, cohort, and case–control studies