| Accuracy measurea | Imaging test (N  = 27 meta-analyses) | Laboratory test (N  = 14 meta-analyses) |
---|---|---|---|
Relative increaseb(95% CI)Pvalue | Relative increaseb(95% CI)Pvalue | ||
Diseased | Sensitivity | 1.13 (1.05 to 1.22) P = 0.002 | 1.01 (0.80 to 1.28) P = 0.92 |
Non-diseased | Specificity | 1.03 (0.86 to 1.24) P = 0.73 | 1.01 (1.00-1.02) P = 0.14 |
Sample size | DOR | 1.05 (0.97 to 1.14) P = 0.23 | 0.94 (0.63 to 1.40) P = 0.76 |
Time since first publication | Sensitivity | 0.88 (0.77 to 1.00) P = 0.05 | 0.94 (0.75 to 1.17) P = 0.57 |
Time since first publication | Specificity | 1.02 (0.87 to 1.19) P = 0.84 | 1.13 (0.80 to 1.58) P = 0.50 |
Time since first publication | DOR* | 0.89 (0.78 to 1.02) P = 0.09 | 0.87 (0.42 to 1.81) P = 0.71 |