Item | Score |
---|---|
1. Study design (selection score) | |
a. Prospective clinical studies (any type) | |
♦ Consecutive enrolment | 2 |
♦ Unspecified/random enrolment | 1 |
b. Autopsy studies | |
♦ Consecutive enrolment | 2 |
♦ Unspecified/random enrolment | 1 |
c. Retrospective reviews (including subgroup analysis) | 1 |
d. Review/editorial | 0 |
e. Case report | 0 |
2. Study objectives (selection score) | |
a. Clear inclusion criteria | |
♦ Aim related to pertussis prevalence or outcomes | 3 |
♦ Related to OIs/general morbidity/respiratory disease but not specific to pertussis | 2 |
♦ Unrelated to clinical pertussis prevalence | 1 |
b. Unclear inclusion criteria | 1 |
3. Diagnosis* (quality of outcome ascertainment) | |
a. Laboratory-confirmed (any specified method/specimen) | 2 |
b. Clinical case definition (consistent with WHO or CDC guidelines) | 1 |
c. Not specified | 0 |
4. Denominator | |
a. Raw data denominator | 2 |
b. Calculated denominator | 1 |
c. No/unclear denominator/investigated < % of cohort for pertussis/exclusion group | 0 |
5. Numerator (Pertussis numbers) | |
a. Raw data numerator | 2 |
b. Calculated numerator | 1 |
c. No/unclear numerator (clinical pertussis not mentioned/tested) | 0 |
6. Assessment of bias (low, high or unclear risk) | |
a. Attrition bias | |
♦ Amount, nature or handling of incomplete outcome data | |
b. Selection bias | |
♦ Representativeness of the cases/cohort (clear reasons for and rates of non-inclusion) |