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Table 2 Inclusion and exclusion criteria for review of evidence on the following: 1. Does early HbA1c predict later complications? 2. What factors predict early HbA1c?

From: Protocol for systematic review of evidence on the determinants and influence of early glycaemic control in childhood-onset type 1 diabetes

Inclusion criteria

Exclusion criteria

For reviews 1 and 2

 

 Interventional studies (RCT’s and non-RCT’s) targeting glycaemic control (within 2 years of diagnosis of T1D) and described an association with health outcomes

Non-human studies

Selection of population based on other diseases/co-morbidities

Adults aged more than 25 years at baseline

Studies on T2D

Quantitative studies not reporting clinical outcomes

Quantitative studies that measured glycaemic control but did not describe an association with outcome variables

 Non-intervention/observational, i.e. cohort and cross-sectional (XS) studies that quantified the association between early glycaemic control (within 2 years of diagnosis of T1D) AND risk of future complications in children and young people aged 0 to 25 years at baseline

 

For review 1: longitudinal studies with a follow-up of ≥5 years from diagnosis

 

For review 2: qualitative studies that give a deeper background understanding on the topic

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