Table 5 Comparison of all lupus nephritis treatments for bone marrow toxicity (cytopenia including leucopenia)

CYC SD

MMF

2.16 (1.14, 4.03)

1.99 (1.13, 3.37)

0.07 (0.01, 0.16)

AZA SD

2.42 (1.01, 7.07)

2.19 (1.01, 5.06)

0.09 (0.00, 0.27)

CYC LD

5.31 (1.26, 24.65)

4.03 (1.23, 10.11)

0.22 (0.02, 0.56)

CYC HD

5.36 (1.95, 18.08)

4.06 (1.81, 8.96)

0.22 (0.07, 0.48)

RTX + MMF SD

3.50 (0.61, 23.14)

2.95 (0.63, 9.43)

0.14 (−0.03, 0.56)

AZA SD

CYC SD

1.11 (0.39, 4.03)

1.09 (0.44, 3.07)

0.01 (−0.11, 0.22)

CYC LD

2.45 (0.51, 13.07)

2.01 (0.56, 5.91)

0.15 (−0.08, 0.50)

CYC HD

2.47 (0.77, 9.99)

2.03 (0.80, 5.38)

0.15 (−0.04, 0.43)

RTX + MMF SD

1.63 (0.26, 11.77)

1.49 (0.30, 5.31)

0.07 (−0.13, 0.49)

CYC LD

AZA SD

2.16 (0.42, 10.83)

1.80 (0.49, 5.39)

0.13 (−0.12, 0.47)

CYC HD

2.20 (0.56, 8.96)

1.83 (0.65, 5.16)

0.13 (−0.10, 0.40)

RTX + MMF SD

1.43 (0.18, 11.42)

1.33 (0.23, 5.33)

0.05 (−0.21, 0.48)

CYC HD

CYC LD

1.01 (0.29, 3.75)

1.01 (0.46, 2.74)

0.00 (−0.28, 0.24)

RTX + MMF SD

0.66 (0.06, 7.15)

0.74 (0.12, 3.78)

−0.07 (−0.48, 0.40)

RTX + MMF SD

CYC HD

0.65 (0.08, 5.36)

0.73 (0.13, 2.81)

−0.08 (−0.41, 0.37)

Random-effects model

Residual deviance

31.43 vs. 33 data points

Deviance information criteria

165.076

Fixed-effects model

Residual deviance

38.78 vs. 33 data points

Deviance information criteria

167.984