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Table 1 Case study A: comparison of PI(E)CO (population, intervention (exposure), comparator, outcome) criteria between the identified systematic review (Alashaik et al. [8]) and our own new review (Haller et al. [6])

From: Use of existing systematic reviews for evidence assessments in infectious disease prevention: a comparative case study

 

Alshaik et al. [8]

Own new review (Haller et al. [6])

Population

Very low birth weight (VLBW) infants

Neonates (no restrictions regarding birth weight or gestational age)

Exposure

Culture-proven sepsis

Sepsis

Comparator

Not explicitly mentioned

No sepsis

Outcome

Moderate to severe neuro developmental impairment, including at least one of the following: cerebral palsy, cognitive delay (cognitive score 2SD < mean), vision loss, deafness

Any neurodevelopmental outcome