Table 4 GRADE for quality of evidence profile
Study ID | Outcomes (number of studies) | Risk of bias | Inconsistency | Indirectness | Imprecision | Publication bias | Quality of evidence |
|---|---|---|---|---|---|---|---|
Chen 2014 [11] | Overall antihypertensive effect (12) | Seriousa | No serious | No serious | No serious | Strongly suspectedb | Low |
Traditional Chinese symptom improved (4) | Seriousa | Seriousc | No serious | No serious | Undetected | Low | |
Decrease of C-reactive protein (1) | Seriousa | No serious | No serious | Seriousd | Strongly suspectedb | Very low | |
Decrease of blood lipid (2) | Seriousa | Seriousc | No serious | Seriousd | Undetected | Very low | |
Decrease of serum uric acid homocysteine (2) | Seriousa | No serious | No serious | Seriousd | Strongly suspectede | Very low | |
Adverse events (1) | Seriousa | No serious | No serious | Seriousd | Strongly suspectede | Very low | |
Wang 2012 [12] | Effect of cerebral hemorrhage (6) | Seriousa | No serious | No serious | No serious | Undetected | Moderate |
Nervous function defect of cerebral infarction score (8) | Seriousa | Seriousc | No serious | No serious | Undetected | Low | |
Adverse events (5) | Seriousa | Seriousc | No serious | No serious | Undetected | Low | |
Guo 2013 [13] | Overall antihypertensive effect (9) | Seriousa | No serious | No serious | No serious | Undetected | Moderate |
Zhou 2012 [22] | Overall antihypertensive effect (6) | Seriousa | No serious | No serious | No serious | Undetected | Moderate |
Traditional Chinese symptom improved (4) | Seriousa | Seriousc | No serious | No serious | Undetected | Low | |
safety (5) | Seriousa | Seriousc | No serious | No serious | Undetected | Low | |
Dong 2011 [23] | Overall antihypertensive effect (6) | Seriousa | No serious | No serious | No serious | Strongly suspectedb | Low |
safety (2) | Seriousa | No serious | No serious | Seriousd | Strongly suspectede | Very low | |
Ren 2006 [24] | Overall antihypertensive effect (11) | Seriousa | No serious | No serious | No serious | Strongly suspectedb | Low |
Dai 2010 [25] | Decrease of systolic blood pressure (9) | Seriousa | No serious | No serious | Seriousd | Undetected | Low |
Decrease of diastolic blood pressure (9) | Seriousa | No serious | No serious | Seriousd | Undetected | Low | |
Du 2014 [26] | Relief of hypertensive headache (10) | Seriousa | No serious | No serious | No serious | Strongly suspectedb | Low |
Relief of hypertensive dizziness (5) | Seriousa | No serious | No serious | No serious | Strongly suspectedb | Low | |
Relief of hypertensive insomnia (3) | Seriousa | No serious | No serious | Seriousd | Strongly suspectedb | Very low | |
Li 2012 [27] | Overall antihypertensive effect (17) | Seriousa | No serious | No serious | No serious | Strongly suspectedb | Low |
Traditional Chinese symptom improved (6) | Seriousa | No serious | No serious | No serious | Strongly suspectedb | Low | |
Changes of pulse pressure (4) | Seriousa | Seriousc | No serious | Seriousd | Undetected | Very low | |
Xiong 2012 [28] | Decrease of systolic blood pressure (3) | Seriousa | Seriousc | No serious | Seriousd | Undetected | Very low |
Decrease of diastolic blood pressure (3) | Seriousa | Seriousc | No serious | Seriousd | Undetected | Very low | |
Adverse events (4) | Seriousa | No serious | No serious | Seriousd | Undetected | Low | |
Wang 2013 [29] | Decrease of systolic blood pressure (3) | Seriousa | Seriousc | No serious | No serious | Undetected | Low |
Decrease of diastolic blood pressure (3) | Seriousa | Seriousc | No serious | No serious | Undetected | Low | |
Wu 2013 [30] | Plasma superoxide dismutase increase (3) | Seriousa | No serious | No serious | Seriousd | Undetected | Low |
Overall antihypertensive effect (9) | Seriousa | Seriousc | No serious | No serious | Undetected | Low |