Table 1 Characteristics of included newborn and child health systematic review (SR) reports and protocols
Characteristic | SR reports % (n) | SR protocols % (n) |
|---|---|---|
Total number of studies | 248 | 76 |
Population included | ||
Child-only studies | 60.9 (151) | 53.9 (41) |
Mixed child/adult studies | 25.8 (64) | 31.6 (24) |
Community/family/maternal intervention/exposure studies | 13.3 (33) | 14.5 (11) |
Type | ||
Cochrane | 59.7 (148) | 34.2 (26) |
Non-Cochrane | 40.3 (100) | 65.8 (50) |
ICD-10 diagnostic category | ||
Infectious disease and parasitic diseases | 10.5 (26) | 15.8 (12) |
Neoplasms (including oncology) | 2.0 (5) | 3.9 (3) |
Blood, blood-forming organs, and the immune mechanism | 1.2 (3) | 2.6 (2) |
Endocrine and nutritional and metabolic disease | 9.7 (24) | 7.9 (6) |
Mental and behavioral disorders | 11.3 (28) | 11.8 (9) |
Nervous system | 4.8 (12) | 6.6 (5) |
Eye and adnexa | 0.4 (1) | 0.0 (0) |
Ear and mastoid process | 1.6 (4) | 1.3 (1) |
Circulatory system | 1.2 (3) | 1.3 (1) |
Respiratory system | 12.1 (30) | 1.3 (1) |
Digestive system | 6.0 (15) | 3.9 (3) |
Skin and subcutaneous tissue | 0.8 (2) | 0.0 (0) |
Musculoskeletal system and connective tissue | 1.2 (3) | 2.6 (2) |
Genitourinary, childbirth, and the puerperium | 11.3 (28) | 3.9 (3) |
Conditions originating in the perinatal period | 7.7 (19) | 5.3 (4) |
Congenital malformation, deformations, and chromosomal abnormalities | 2.4 (6) | 2.6 (2) |
Symptoms, signs, and abnormal clinical laboratory findings not elsewhere classified | 1.2 (3) | 2.6 (2) |
Injury, poisoning, and consequences of external causes | 5.2 (13) | 7.9 (6) |
External causes of morbidity and mortality | 0.0 (0) | 0.0 (0) |
Factors influencing health status and contact with health services | 0.8 (2) | 10.5 (8) |
Oral health | 0.0 (0) | 0.0 (0) |
No explicit medical condition | 8.1 (20) | 5.3 (4) |
Other | 0.4 (1) | 2.6 (2) |
Intervention type | ||
Drug/natural health products | 49.2 (122) | 36.8 (28) |
Device | 8.5 (21) | 2.6 (2) |
Surgery or radiotherapy | 7.7 (19) | 7.9 (6) |
Rehabilitation or psycho-social | 14.5 (36) | 9.2 (7) |
Vaccine | 0.8 (2) | 2.6 (2) |
Communication, organizational, or education | 9.7 (24) | 22.4 (17) |
Prevention or screening | 2.4 (6) | 3.9 (3) |
Complex intervention (>1 interventions) | 2.4 (6) | 2.6 (2) |
Other | 5.6 (14) | 17.1 (13) |
No explicit exposure or intervention | 5.2 (13) | 5.3 (4) |
Comparison type | ||
Drug/natural health products | 43.5 (108) | 31.6 (24) |
Device | 7.3 (18) | 2.6 (2) |
Surgery or radiotherapy | 4.8 (12) | 5.3 (4) |
Rehabilitation or psycho-social | 9.7 (24) | 6.6 (5) |
Vaccine | 0.8 (2) | 2.6 (2) |
Communication, organizational, or education | 5.2 (13) | 14.5 (11) |
Prevention or screening | 0.8 (2) | 2.6 (2) |
Complex intervention (>1 interventions) | 2.0 (5) | 0.0 (0) |
Other | 8.1 (20) | 15.8 (12) |
No explicit exposure or intervention | 26.2 (65) | 28.9 (22) |