A systematic review of neonatal treatment intensity scores and their potential application in low-resource setting hospitals for predicting mortality, morbidity and estimating resource use

Table 2 Characteristics of studies included in the review

Study	Study dates	Objective*	Setting	Sample size	In-hospital mortality^\|\|
Georgieff, 1989 [40]	1987	Validation (TISS)^‡	1 NICU†, USA	55	0
Gray, 1992 [19]	1989–1990	Development (NTISS)^§	3 NICUs†, USA	1768	114
Davies, 1995 [33]	Not reported	Validation (NTISS)^§	1 NICU†, South Africa	50	8
Eriksson, 2002 [34]	1991–1995	Validation (NTISS)^§	2 NICUs†, Sweden	240	39
Zupancic, 2002 [35]	1998 & 1999	Validation (NTISS)^§	1 NICU†, USA	154	Not reported
Mendes, 2006 [35]	2004	Validation (NTISS)^§	2 NICUs†, Brazil	96	9
Rojas, 2011 [37]	2007	Validation (NTISS)^§	1 NICU†, 1 intermediate unit, Colombia	22	Not reported
Oygur, 2012 [38]	2006–2010	Validation (NTISS)^§	1 NICU†, Turkey	364	103
Shah, 2015 [32]	2010–2012	Development (unnamed)	23 NICU†s, Canada	9978	650
Wu,2015 [39]	2007–2011	Validation (NTISS)^§	1 NICU†, Taiwan	172	18

*Study objective, model development (creation of a new model) or validation (application of an existing score/model to an external population)
†Neonatal intensive care unit
‡Therapeutic intervention scoring system
§Neonatal therapeutic intervention scoring system
||Primary outcome for the review. Data was however extracted on all outcomes reported by the authors

ISSN: 2046-4053