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Table 3 Completeness of primary outcome pre-specification in a random sample of 150 SRs registered in PROSPERO between April 1, 2017 and September 30, 2017

From: Registration of systematic reviews in PROSPERO: 30,000 records and counting

Components of outcome

Number (%) all SRs

Number (%) therapeutic SRs

Number (%) non-therapeutic SRs

Risk ratio (95% CI)

n = 150

n = 78

n = 72

Domain

150 (100%)

78 (100%)

72 (100%)

NA

Specific measurement

65 (43%)

35 (45%)

30 (42%)

1.08 (0.75, 1.56)

Specific metric

63 (42%)

31 (40%)

32 (44%)

0.89 (0.61, 1.30)

Method of aggregation

69 (46%)

36 (46%)

33 (46%)

1.01 (0.71, 1.42)

Time point

25 (17%)

20 (26%)

5 (7%)

3.69 (1.46, 9.32)

Only domain specified

44 (29%)

21 (27%)

23 (32%)

0.84 (0.51, 1.39)

Outcome completely pre-specified

9 (6%)

7 (9%)

2 (3%)

3.23 (0.69, 15.04)

  1. CI confidence interval, NA not applicable, SR systematic review