Table 3 Summary estimates of diagnostic test accuracy by field strategy and variations by reference standard
Imaging strategy | Non-mydriatic | Mydriatic | |||||||
|---|---|---|---|---|---|---|---|---|---|
Reference—7F ETDRSb | Reference—DF slit lamp examination | Reference—7F ETDRS | Reference—DF slit lamp examination | ||||||
Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | ||
Overall estimate | 87% | 96% | 86% | 91% | 86% | 96% | 86% | 87% | |
(85–89%)a (8) | (95–97) (6) | (85–88%) (10) | (91–92%) (10) | (84–89%) (5) | (95–97%) (5) | (85–87%) (12) | (86–88%) (12) | ||
Field strategy | 1F 1 field | 79% | 96% | 78% | 89% | 77% | 96% | 80% | 91% |
(74–83%) (2) | (95–98%) (2) | (75–80%) (6) | (88–90%) (6) | (70–82%) (1) | (95–99%) (1) | (78–83%) (6) | (90–92%) (5) | ||
2F 2 field | 90% | 96% | 92% | 93% | 83% | 95% | 86% | 75% | |
(86–93%) (2) | (94–98%) (2) | (90–93%) (2) | (92–94%) (2) | (80–87%) (2) | (93–97%) (2) | (84–88%) (4) | (74–77%) (4) | ||
> 2F > 2 field | 88% | 95% | 90% | 94% | 91% | 93% | 93% | 95% | |
(85–91%) (4) | (93–97%) (4) | (83–96%) (2) | (92–96%) (2) | (88–94%) (2) | (90–96%) (2) | (90–95%) (2) | (93–97%) (2) | ||