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Table 4 Summary estimates of diagnostic test accuracy by field strategy, by index test grader, by pupil status and by setting

From: Systematic review and meta-analysis of diagnostic accuracy of detection of any level of diabetic retinopathy using digital retinal imaging

Imaging strategy

Index grader

Non-mydriatic

Mydriatic

Sensitivity

Specificity

Sensitivity

Specificity

Estimate

(95% CI)

Number of studies

Estimate

(95% CI)

Number of studies

Estimate

(95% CI)

Number of studies

Estimate

(95% CI)

Number of studies

Overall estimates

 

86%

(85–87%)

18

93%

(92–93%)

18

86%

(85–87%)

17

90%

(89–90%)

17

By index test grader

Ophthalmologist

82%

(80–84%)

7

94%

(94–95%)

7

87%

(85–89%)

9

93%

(92–94%)

9

Retinologist

90%

(89–92%)

7

94%

(93–95%)

7

69%

(62–75%)

2

93%

(91–96%)

2

Retinal reader

89%

(86–93%)

3

91%

(88–94%)

3

86%

(84–88%)

4

92%

(91–94%)

4

SpR registrar

78%

(75–81%)

1

81%

(79–82%)

1

86%

(84–89%)

2

70%

(68–72%)

2

By field strategy

1F

Ophthalmologist

73%

(69–77%)

3

96%

(94–97%)

3

78%

(75–81%)

4

94%

(92–95%)

4

Retinologist

79%

(75–84%)

3

81%

(76–86%)

3

69%

(62–75%)

2

93%

(91–96%)

2

Retinal reader

83%

(77–87%)

1

91%

(88–94%)

1

86%

(81–89%)

1

91%

(88–93%)

1

SpR registrar

78%

(75–81%)

1

81%

(79–82%)

1

No data

–

No data

–

2F

Ophthalmologist

87%

(84–90%)

2

90%

(88–92%)

 

86%

(83–89%)

2

86%

(84–88%)

2

Retinologist

93%

(91–95%)

2

96%

(94–97%)

2

No data

 

No data

 

Retinal reader

No data

–

No data

–

82%

(78–85%)

2

95%

(92–97%)

2

SpR registrar

No data

–

No data

–

86%

(84–89%)

2

70%

(68–72%)

2

> 2F

Ophthalmologist

84%

(79–88%)

2

97% (95–98%)

2

93%

(91–96%)

3

96%

(94–98%)

2

Retinologist

82%

(75–90%)

2

86% (8–90%)

2

No data

–

No data

–

Retinal reader

93%

(89–96%)

2

No data

–

90%

(86–93%)

1

90%

(87–92%)

1

SpR registrar

No data

–

No data

–

No data

–

No data

–

By setting

Primary

85%

(83–86%)

8

92% (91–92%)

8

82%

(80–84%)

6

91%

(90–92%)

6

Other (secondary or tertiary)

90%

(88–91%)

10

95% (94–96%)

10

87%

(86–89%)

11

89%

(88–90%)

11