Study characteristic | Specific items |
---|---|
Study identifiers | Title, authors, journal, publication year, county of publication, and sponsorship |
Study design | Number of animals assigned to each experimental and control group and method of SNHL induction |
Animal model characteristics | Animal species, gender, strain, age, method of SNHL induction, and immune status |
Intervention characteristics | Source of MSCs, MSC identifiers including plastic adherence, positive/negative markers, differentiation, cell expansion media, passage number, cell dose, method of delivery, timing relative to SNHL induction, and frequency of MSC administration |
Outcome measures | Method of assessing hearing outcome and timing of data collection relative to SNHL induction |
Other | Long-term outcomes, type of control, MSC side effects (animal survival) |