Table 2 Draft search strategy (MEDLINE)

1

exp Physicians, Primary Care/

2

exp General Practitioners/

3

exp Family Practice/

4

exp Physicians, Family/

5

exp Practice Patterns, Physicians’/

6

exp Nurse Practitioners/

7

exp Nurse Clinicians/

8

exp Primary Health Care/

9

exp Ambulatory Care/

10

exp Community Health Services/

11

exp Community Medicine/

12

exp Office Visits/

13

physician*.mp.

14

primary care physician*.mp.

15

family physician*.mp.

16

family doctor*.mp.

17

(general adj2 physician*).mp.

18

(general adj2 practitioner*).mp.

19

(family adj2 practitioner*).mp.

20

(primary care adj2 practitioner*).mp.

21

(nurse* adj2 clinician*).mp.

22

(nurse adj2 practitioner*).mp.

23

family practice*.mp.

24

family medicine.mp.

25

general practice*.mp.

26

outpatient practice*.mp.

27

primary care.mp.

28

primary care setting*.mp.

29

public sector healthcare.mp.

30

office-based.mp.

31

(private adj2 office*).mp.

32

(physician* adj2 office*).mp.

33

(office* adj2 visit*).mp.

34

(community adj3 care).mp.

35

(community adj3 healthcare).mp.

36

(community adj3 treatment).mp.

37

or/1-36

38

exp Opiate Substitution Treatment/

39

37 and 38

40

exp BUPRENORPHINE/

41

exp BUPRENORPHINE, NALOXONE DRUG COMBINATION/

42

exp Naloxone/

43

exp METHADONE/

44

(opioid adj2 treatment).mp.

45

(opioid adj2 therap*).mp.

46

(opioid adj2 substitution).mp.

47

(opioid adj2 replacement).mp.

48

(opioid adj2 maintenance).mp.

49

(opiate adj2 treatment).mp.

50

(opiate adj2 therap*).mp.

51

(opiate adj2 substitution).mp.

52

(opiate adj2 replacement).mp.

53

methadone.mp.

54

(methadone adj2 treatment).mp.

55

(methadone adj2 therap*).mp.

56

(methadone adj2 substitution).mp.

57

(methadone adj2 replacement).mp.

58

Buprenorphine.mp.

59

(buprenorphine adj2 treatment).mp.

60

(buprenorphine adj2 therap*).mp.

61

(buprenorphine adj2 substitution).mp.

62

(buprenorphine adj2 replacement).mp.

63

naloxone.mp.

64

(naloxone adj2 treatment).mp.

65

(naloxone adj2 therap*).mp.

66

(naloxone adj2 substitution).mp.

67

(naloxone adj2 replacement).mp.

68

(buprenorphine naloxone adj2 treatment).mp.

69

(buprenorphine naloxone adj2 therap*).mp.

70

(buprenorphine naloxone adj2 substitution).mp.

71

(buprenorphine naloxone adj2 replacement).mp.

72

(medication assisted adj2 treatment).mp.

73

(medication assisted adj2 therap*).mp.

74

(maintenance adj2 treatment).mp.

75

(maintenance adj2 therap*).mp.

76

(substitution adj2 therap*).mp.

77

opioid agonist*.mp.

78

or/40-77

79

exp Opioid-Related Disorders/

80

exp Heroin Dependence/

81

exp Morphine Dependence/

82

exp Opium Dependence/

83

“opioid use”.mp.

84

“opioid use disorder*”.mp.

85

Opioid related disorder*.mp.

86

(opioid adj2 disorder*).mp.

87

(opioid adj2 addict*).mp.

88

(opioid adj2 abuse).mp.

89

(opioid adj2 dependen*).mp.

90

or/79-89

91

37 and 78 and 90

92

39 or 91

93

limit 92 to (english or french)