Table 3 Topics of the 152 projects with publicly available data on the Systematic Review Data Repository (SRDR) website as of November 12, 2019, categorized by health area

Mental and behavioral disorders (31 projects)

Adverse behavioral effects of caffeine consumption

Age-related cognitive decline, mild cognitive impairment, and clinical Alzheimer’s-type dementia

Aggressive behavior in psychiatric patients

Agitation and aggression in dementia

Antipsychotics for children and young adults

Anxiety in children

Attention deficit hyperactivity disorder (ADHD) in children and adolescents

Atypical antipsychotics

Autism spectrum disorder

Autism spectrum disorder

Autism spectrum disorder

Autism spectrum disorder

Binge-eating disorder

Bipolar disorder

Developmental disabilities, intellectual disability, and autism spectrum disorder

Disparities within serious mental illness

Disruptive behavior in children and adolescents

Insomnia disorder

Major depressive disorder

Major depressive disorder

Major depressive disorder

Major depressive disorder

Major depressive disorder in adults

Major depressive disorder in older adults

Management strategies to reduce psychiatric readmissions

Mental health care for children and adolescents

Opioid use disorder

Post-acute coronary syndrome depression

Posttraumatic stress disorder (PTSD)

Schizophrenia

Treatment-resistant depression

Diseases of the eye and ocular adnexa (23 projects)

Acanthamoeba keratitis

Active trachoma

Active trachoma

Bacterial keratitis

Cataract

Cataract and glaucoma

Central serous chorioretinopathy

Chronic angle closure glaucoma

Chronic non-infectious uveitis

Glaucoma

Glaucoma

Glaucoma

Glaucoma

Intermittent exotropia

Neovascular age-related macular degeneration

Neovascular age-related macular degeneration

Onchocerciasis

Optic neuritis

Pigmentary glaucoma

Primary congenital glaucoma

Retinal prostheses

Retinitis pigmentosa

Trachoma trichiasis

Neoplasms (13 projects)

Basal cell and squamous cell carcinoma of the skin

Basal cell carcinoma

Decision aids for cancer screening and treatment

Hepatocellular carcinoma

Infantile hemangioma

Lymphoma, colorectal cancer, and head and neck cancer

Metastatic breast cancer

Non-metastatic muscle-invasive bladder cancer

Non-muscle-invasive bladder cancer

Pancreatic adenocarcinoma

Primary breast cancer

Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women

Small cell lung cancer

Diseases of the musculoskeletal system and connective tissue (12 projects)

Acute pain

Adverse bone and calcium balance effects of caffeine consumption

Chronic pain

Common hip fractures

Early rheumatoid arthritis

Fibromyalgia

Fractures in men and women with low bone density or osteoporosis

Low-back pain

Low-back pain

Lower limb prosthesis

Osteoporosis fracture prevention

Primary and secondary osteoarthritis of the knee

Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified (10 projects)

Acute adverse effects of caffeine consumption

Dietary fiber and health

Dietary sugars and health

Home-based primary care interventions

Low calorie sweeteners

Low calorie sweeteners

Palliative care

Routine preoperative testing

Silicone gel breast implants

Total Worker Health® (TWH)

Diseases of the genitourinary system (9 projects)

Genitourinary complaints in post-menopausal women

Benign prostatic hyperplasia

Chronic kidney disease

Infertility

Polycystic ovary syndrome

Renal transplantation

Stress urinary incontinence in women

Urinary incontinence in adult women

Uterine fibroids

Diseases of the circulatory system (8 projects)

Adverse cardiovascular effects of caffeine consumption

Atrial fibrillation

Coronary artery disease

Lower extremity chronic venous disease (LECVD)

Renal artery stenosis

Stroke prevention in patients with atrial fibrillation

Venous thromboembolism prophylaxis

Venous thromboembolism prophylaxis in orthopedic surgery

Certain infectious and parasitic diseases (7 projects)

Clostridium difficile infection

Clostridium difficile infection

Healthcare-associated infections

Pre-exposure prophylaxis for prevention of HIV infection

Screening for hepatitis B virus infection in pregnant women

Screening for HIV infection in asymptomatic, nonpregnant adolescents and adults

Screening for HIV infection in pregnant women

Diseases of the respiratory system (7 projects)

Acute exacerbations of chronic obstructive pulmonary disease (COPD) in adults

Acute respiratory tract infections

Asthma

Asthma

Asthma

Asthma

Obstructive sleep-disordered breathing or recurrent throat infection in children

Factors influencing health status and contact with health services (6 projects)

Health disparities

Health information exchange

Health services

Safety in nursing home settings

Telehealth

Telehealth

Injury, poisoning, and certain other consequences of external causes (5 projects)

Field triage of trauma

Physiologic predictors of severe injury

Suspected opioid overdose

Screening for elevated blood lead levels in children

Screening for elevated blood lead levels in pregnant women

Endocrine, nutritional, and metabolic diseases (4 projects)

Diabetes

Diabetes

Diabetes

Type 2 diabetes

Pregnancy, childbirth, and the puerperium (4 projects)

Adverse reproductive and developmental effects of caffeine consumption

Breastfeeding programs, policies, uptake and maternal health outcomes in developed countries

Gestational diabetes

Postpartum hemorrhage

Diseases of the digestive system (3 projects)

Bariatric surgery in the Medicare population

Fecal incontinence

Non-alcoholic fatty liver disease (NAFLD)

Congenital malformations, deformations, and chromosomal abnormalities (1 project)

Ankyloglossia

Diseases of the ear and mastoid process (1 project)

Tympanostomy tubes in children

Codes for special purposes (1 project)

Privacy and genetic information

Other—methodology (7 projects)

Decision and simulation modeling

Examination of loss of information related to outcome choice in meta-analyses

Indexing of SRDR projects (project for the current study)

Reliability of systematic reviews addressing corneal diseases

Summary of outcomes in clinical trials addressing HIV/AIDS

Summary of outcomes in clinical trials in ophthalmology

Summary of outcomes in systematic reviews addressing dry eye