Table 1 Characteristics of primary studies (N  = 859) across and within the included meta-analyses (N  = 46)

Across all meta-analyses

Number of diseased

33

17-63

0-1,358

Number of non-diseased

36

18-100

0-49,973

Sample size

87

45-185

3-50,008

Time since first publication (years)

6

3-10

0-42

Median of the median

Interquartile range of medians

Min-max of the median

Within meta-analyses

Number of diseased

31

18-41

5-154

Number of non-diseased

38

18-87

0-11,276

Sample size

94

46-332

20-11,281

Time since first publication (years)

5

4-11

0-26