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Table 1 Studies with provisional support and consideration to share individual patient data

From: Erratum to: Study protocol: differential effects of diet and physical activity based interventions in pregnancy on maternal and fetal outcomes: individual patient data (IPD) meta-analysis and health economic evaluation

Study Year

Country

Study Characteristics

Outcomes

Sample size

Maternal

Fetal

Althuizen 2012

Netherlands

Ethnically diverse , no BMI restrictions, age n.r., GA at inclusion < 14 wks, glucose status n.r., other risk factors: n.r.

GWG, GDM, preterm delivery, CS

birth weight, macrosomia

269

Barakat 2009

Spain

Caucasian, BMI restrictions n.r., age 25–35 yrs, GA at inclusion n.r. (total at least 26 wks intervention), glucose status n.r., no known pre-existing health problems

GWG, GA, preterm delivery

birth weight, LGA, SGA, AS, macrosomia (>4000g)

142

Barakat 2011

Spain

Spanish (white), BMI restrictions n.r., age 23–38 yrs, GA at inclusion 1st prenatal visit, glucose status n.r., no known pre-existing health problems

GWG, GA CS, vaginal delivery

birth weight, AS

80

Barakat 2013

Spain

Caucasian, no BMI restrictions, age n.r., GA at inclusion <10 wks, glucose status n.r., no known pre-existing health problems

GWG, GA, GDM, PIH, preterm delivery

birth weight, AS

765

Bogaerts 2012

Belgium

Ethnically diverse , BMI ≥ 29 kg/m2, age n.r., GA at inclusion < 15 wks, nondiabetic, other risk factors: n.r

GWG, GA, PE, PIH, GDM, IOL, CS, vaginal delivery

birth weight, AS

197

Cavalcante 2009

Brazil

Race n.r., no morbid obesity, age restrictions n.r., GA at inclusion 16–20 wks, glucose status n.r., no known pre-existing health problems

GWG, preterm delivery

birth weight

71

Clapp 1997

USA

Race n.r., no morbid obesity, age restrictions n.r., GA at inclusion 8 wks, glucose status n.r., no known pre-existing health problems

GWG

birth weight

51

Clapp 2000

USA

Race n.r., no morbid obesity, age restrictions n.r., GA at inclusion 8 wks, glucose status n.r., no known pre-existing health problems

GWG, GA

birth weight

12

Dodd 2014

Australia

Race n.r., BMI ≥ 25 kg/m2, age restrictions n.r., GA at inclusion <20 wks, nondiabetic, other risk factors: n.r.

PE, PIH, GDM, IOL, CS, Preterm delivery

LGA, macrosomia (>4000g), hypoglycaemia, shoulder dystocia, admission to NICU

2,212

El Beltagy 2013

Egypt

Race n.r., BMI: obese, age restrictions n.r., GA at inclusion: first antenatal visit, glucose status n.r., other risk factors: n.r.

GWG, GDM

birth weight, macrosomia

100

Grant 2013

Canada

Race : predominantly non-Caucasian, BMI restrictions n.r., age >18 yrs, GA at inclusion n.r., glucose status: impaired glucose tolerance or GDM, no known pre-existing health problems

GWG

birth weight, macrosomia

47

Guelinckx 2010

Belgium

Caucasian, BMI ≥ 29 kg/m2, age restrictions n.r., GA at inclusion <15 wks, nondiabetic, no known pre-existing health problems

GWG, GA, PE, PIH, IOL, CS

birth weight, LGA

85

Haakstad 2011

Norway

Race n.r., BMI restrictions n.r., age restrictions n.r., GA at inclusion <24 wks, glucose status n.r., no known pre-existing health problems

GWG

 

105

Hui 2006

Canada

Ethnically diverse, BMI restrictions n.r., age restrictions n.r., GA at inclusion <26 wks, nondiabetic, no known pre-existing health problems

GWG, GA, GDM

birth weight, LGA

45

Hui 2011

Canada

Race n.r., BMI restrictions n.r., age restrictions n.r., GA at inclusion 20–26 wks, nondiabetic, no known pre-existing health problems

GWG, GA, GDM, CS

birth weight, LGA

224

Jackson 2010

USA

Ethnically diverse, BMI restrictions n.r., age >18 yrs, GA at inclusion <26 wks, glucose status n.r., other risk factors: n.r.

GWG

 

321

Jeffries 2009

Australia

Race n.r., BMI restrictions none, age >18 - <45 yrs, GA at inclusion <14 wks, nondiabetic, other risk factors: n.r.

GWG, PE, PIH, GDM , preterm delivery, CS

birth weight, LGA, SGA, hypoglycaemia, shoulder dystocia

236

Khaledan 2010

Iran

Race n.r., BMI restrictions n.r., age restrictions n.r., GA at inclusion 24–32 wks, no Diabetes Mellitus type 1 (DM1) with poor control, no known pre-existing health problems

GWG, GA, CS

birth weight

39

Khoury 2005

Norway

Caucasian, BMI 19–32 kg/m2. age 21–38 yrs, GA at inclusion 17–20 wks, nondiabetic, no known pre-existing health problems

GWG, PE, preterm delivery

birth weight, SGA, intra-uterine death

290

Luoto 2011

Finland

Race n.r., BMI >17 kg/m2, age >18 yrs, GA at inclusion 8–12 wks, nondiabetic, no known pre-existing health problems

GWG, GA, PE, GDM

birth weight, LGA, SGA

399

Nascimento 2011

Brazil

Race n.r., BMI >26 kg/m2, age >18 yrs, GA at inclusion 14–24 wks, nondiabetic, no known pre-existing health problems

GWG, PIH, GDM, CS

birth weight, AS, LGA, SGA

82

Ong 2009

Australia

Race n.r., obese, age restrictions n.r., GA at inclusion 18 wks, nondiabetic, other risk factors: n.r.

GWG

 

12

Oostdam 2012

Netherlands

Ethnically diverse, BMI ≥ 25.0 kg/m2, age > 18 yrs, GA at inclusion <20 wks, nondiabetic, no known pre-existing health problems

GWG, GDM

birth weight

124

Petrella 2013

Italy

Ethnically diverse , BMI ≥ 25.0 kg/m2, age > 18 yrs, GA at inclusion 12 wks, nondiabetic, no known pre-existing health problems

GWG, GDM, PIH, preterm delivery

 

63

Phelan 2011

USA

Ethnically diverse, BMI ≥19.8-26.0 kg/m2, age >18 yrs, GA at inclusion 10–16 wks, glucose status n.r., no known pre-existing health problems

GWG, GA, PE, PIH, GDM, preterm delivery, CS

birth weight, macrosomia, birth weight <2500g

401

Poston 2013

United Kingdom

Race: n.r., BMI ≥30 kg/m2, age restrictions n.r., GA at inclusion >15+0 weeks and <17+6, , nondiabetic, no known pre-existing health problems

GA, GWG, PE, GDM, mode of delivery

Birth weight, macrosomia, still birth

183

Prevedel 2003

Brazil

Race: n.r., BMI restrictions n.r., age restrictions n.r. (primiparous or adolescents), GA at inclusion 16–20 wks, glucose status n.a., no known pre-existing health problems

GWG, preterm delivery

birth weight, SGA

41

Rauh 2013

Germany

Race: n.r., BMI ≥18.5 kg/m2, age ≥18 yrs, GA at inclusion <18 wks, nondiabetic, no known pre-existing health problems

GWG, GDM, IOL, CS, preterm delivery

Birth weight LGA, SGA

250

Renault 2013

Denmark

Race: predominantly Caucasian, BMI ≥30 kg/m2, age >18 yrs, GA at inclusion <16 wks, nondiabetic, no known pre-existing health problems

GWG, GDM, PIH,PE,IOL, CS, preterm delivery

Birth weight, SGA, LGA, Birth weight >4000g

425

Sagedal 2014

Norway

Race: n.r., BMI ≥19 kg/m2, age ≥18 yrs, GA at inclusion <20 wks, nondiabetic, no known pre-existing health problems

GWG, GDM, CS

LGA

606

Stafne 2012

Norway

White, no BMI restrictions, age >18 yrs, GA at inclusion 18–22 wks, nondiabetic, no known pre-existing health problems

GA, PE, PIH, GDM, CS

birth weight, AS, LGA, admission to NICU

855

Vesco 2013

USA

Race: n.r., BMI ≥30 kg/m2, age n.r., GA at inclusion <20 wks, nondiabetic, no known pre-existing health problems

GWG, GA, PE, PIH, GDM, CS, preterm delivery

birth weight, LGA, SGA, macrosomia (4000g)

114

Vinter 2011

Denmark

Caucasian, BMI 30–45 kg/m2, age 18–40 yrs, GA at inclusion 10–14 wks, nondiabetic, no known pre-existing health problems

GWG, PE, PIH, GDM, CS

LGA, admission to NICU

360

Vitolo 2011

Brasil

Race: n.r., BMI restrictions: none, age <35yrs, GA at inclusion 10–29 wks, nondiagetic, no known pre-existing health problems

GWG,PE, PIH, GDM, preterm birth

birth weight

315

Walsh 2012

Ireland

Race: n.r., BMI restrictions n.r., age >18 yrs, GA at inclusion < 18 wks, nondiabetic, no known pre-existing health problems

GWG, GA, preterm delivery, IOL, CS

birth weight, macrosomia

800

Wolff 2008

Denmark

Caucasian, BMI ≥30 kg/m2, age >18 - <45 yrs, GA at inclusion <18 wks, nondiabetic, no known pre-existing health problems

GWG PE, PIH, GDM , CS

birth weight

66

Yeo 2012

USA

Ethnically diverse, BMI >19.8 kg/m2, no age restrictions, GA at inclusion 18 wks, nondiabetic, no known pre-existing health problems

GWG, PE, PIH

birth weight

17

  1. AS Apgar score, CS Caesarean section, GA Gestational Age, GDM Gestational diabetes mellitus, GWG Gestational weight gain, IOL Induction of labour, LGA Large for gestational age, NICU Neonatal Intensive Care Unit, n.r. not reported, PE Pre eclampsia, PIH Pregnancy Induced hypertension, RDS Respiratory Distress Syndrome, SGA Small for gestational age