Table 2 Significant differencesa between treatments of lupus nephritis for a composite end-point of renal remission or renal response (includes partial remission, complete remission and renal response)
Treatment | Reference | Odds ratio (95 % CrI) | Relative risk (95 % CrI) | Risk difference % (95 % Crl) |
|---|---|---|---|---|
CYC | PRED | 2.35 (1.28, 4.23) | 1.60 (1.60, 2.24) | 0.21 (0.06, 0.34) |
MMF | 3.26 (1.57, 6.72) | 1.82 (1.82, 2.60) | 0.28 (0.11, 0.44) | |
TAC | 2.51 (1.11, 5.76) | 1.64 (1.64, 2.44) | 0.22 (0.03, 0.41) | |
CSA | 5.69 (2.02, 17.61) | 2.15 (2.15, 3.18) | 0.40 (0.17, 0.58) | |
CYC LD | CYC | 0.32 (0.10, 0.89) | 0.51 (0.51, 0.95) | −0.26 (−0.45, −0.03) |
CYC LD | MMF | 0.23 (0.08, 0.61) | 0.45 (0.45, 0.81) | −0.34 (−0.53, −0.12) |
CYC HD | 0.40 (0.20, 0.74) | 0.65 (0.65, 0.89) | −0.22 (−0.38, −0.07) | |
CSA | AZA | 3.20 (1.04, 10.19) | 1.53 (1.53, 2.39) | 0.26 (0.01, 0.47) |
CYC LD | TAC | 0.30 (0.09, 0.91) | 0.50 (0.50, 0.95) | −0.28 (−0.50, −0.02) |
PLASMA | CSA | 0.19 (0.04, 0.92) | 0.49 (0.49, 0.97) | −0.38 (−0.66, −0.02) |
CYC LD | 0.13 (0.03, 0.52) | 0.38 (0.38, 0.76) | −0.45 (−0.69, −0.15) | |
CYC HD | 0.23 (0.06, 0.72) | 0.55 (0.55, 0.87) | −0.33 (−0.57, −0.08) | |
CYC HD | 0.23 (0.06, 0.72) | 0.55 (0.55, 0.87) | −0.33 (−0.57, −0.08) | |
Random-effects model | Residual deviance | 82.2 vs. 77 data points | ||
Deviance information criteria | 389.332 | |||
Fixed-effects model | Residual Deviance | 88.8 vs. 77 data points | ||
Deviance information criteria | 390.488 |