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Table 2 Characteristics of the included systematic reviews

From: Chinese herbal medicine for the treatment of primary hypertension: a methodology overview of systematic reviews

Researchers and publication time

Types of included studies

Number of studies (total sample)

Age

Interventions

Follow-up time

Evaluation criteria of methodology

Conclusions

Treatment group

Control group

Chen 2014 [11]

RCT

12 (1001)

39–80

Banxia baizhu tianma tang + conventional medicine

Conventional medicine

Jadad

As compared with conventional medicine banxia baizhu tianma tang combined with it can improve the clinical curative effect in treating high blood pressure

Wang 2012 [12]

RCT

11 (981)

36–86

Danshen injection + control group

Hemostatic agents、dehydrator, regulation of blood pressure, brain cell protective agent

6 months

Jadad

Danshen injection has a certain treatment effect in treating hypertensive cerebral hemorrhage, and the earlier the better

Guo 2013 [13]

RCT

14 (1364)

Liuwei dihuang pill + conventional medicine

Conventional medicine

Jadad

The whole therapy effect of liuwei dihuang pill combined with conventional medicine is better than that of single conventional medicine, and so do the SBP and DBP

Zhou 2012 [22]

RCT

8 (554)

Tianma gouteng yin + captopril

Captopril

Jadad

Compared with single captopril, the clinical efficacy of tianma gouteng yin combined with captopril is more better, which can improve symptoms with better blood pressure effect

Dong 2011 [23]

RCT

6 (543)

Tianma gouteng yin + captopril

Captopril

Jadad

Tianma gouteng yin may obtain better treatment result and more security than enalapril in treatment of essential hypertension

Ren 2006 [24]

RCT

11 (1010)

TCM combination therapy including Chinese herb medicine, Chinese patent medicines, acupuncture, etc.) + conventional medicine

Conventional medicine

Jadad

Traditional Chinese medicine may have similar effect with conventional medicine in primary hypertension therapy

Dai 2010 [25]

RCT

9 (655)

Therapied by Chinese herb medicine or combined with conventional medicine

Conventional medicine

Jadad

Traditional Chinese medicine can reduce the SBP and DBP effectively, improve efficiency, integrated Chinese and Western treatment is more better

Du 2014 [26]

RCT

10 (1777)

Yangxue qingnao granules + conventional medicine

Conventional medicine

Risk of bias

Yangxue qingnao granules can significantly improve headache, dizziness, insomnia symptoms of high blood pressure

Li 2012 [27]

RCT

17 (1323)

TCM combination therapy including Chinese herb medicine compound, Chinese patent medicines, acupuncture, etc.) + conventional medicine

Conventional medicine

Jadad

Traditional Chinese medicine has a certain effect in treatment of elderly hypertension patients and reduced pulse pressure with symptoms reduced

Xiong 2012 [28]

RCT

16 (1424)

19–78

Banxia baizhu tianma tang + blood pressure drugs

Blood pressure drugs or placebo

Risk of bias

Banxia baizhu tianma tang has better antihypertensive effect

Wang 2013 [29]

RCT

22 (1808)

30–74

Tianma gouteng yin + blood pressure drugs

Blood pressure drugs

Risk of bias

The efficacy and safety evidence of tianma gouteng yin, as an adjunct of blood pressure medicine, needs further study

Wu 2013 [30]

RCT

9 (784)

Tianma gouteng yin

Conventional medicine

Jadad

Tianma gouteng yin can effectively lower the SBP and DBP

  1. “–”means do not report related information