Skip to main content

Table 2 Examples of outcomes associated with treatment of behavioral and psychological symptoms of dementia (BPSD)

From: Comparative safety and efficacy of pharmacological and non-pharmacological interventions for the behavioral and psychological symptoms of dementia: protocol for a systematic review and network meta-analysis

Outcomes of treatment efficacy

 

Aggression*

 

Agitation

 

Depression

 

Apathy

 

Anxiety

 

Night-time behaviors

 

Motor disturbances

 

Irritability

 

Disinhibition

 

Psychosis (delusions and hallucinations)

 

Appetite and eating abnormalities

 

Caregiver well-being

 

Overall quality of life (both patient and caregiver)

 

Improvement in function

 

Admission to skilled nursing facility

 

Outcomes of treatment safety

 

Fractures*

 

Falls

 

Stroke

 

Mortality

 

Prolonged QTc interval

 

Myocardial infarction

 

Pneumonia

 

Deterioration in cognition

 

Hyperprolactinemia

 

Weight gain

 

Somnolence

 

Hypotension

 

Edema

 

Cytopenia

 

Extrapyramidal side effects (e.g., tardive dyskinesia)

 

Hospitalization

 

Admission to intensive care unit (ICU)

 
  1. *Primary outcome of interest