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Table 1 Level of quality of evidence according to GRADE [26]

From: Effects of aerobic exercise in the treatment of older adults with chronic musculoskeletal pain: a protocol of a systematic review

GRADE Score

Quality

Interpretation

≤ 1

Very low

Any estimation of effect is highly uncertain

2

Low

Further research is likely to have a significant impact on our confidence in the estimated treatment effect and may change the estimate

3

Moderate

Further research is likely to have a significant impact on our confidence in the estimated treatment effect and may change the estimate

≥ 4

High

It is very unlikely that further research will alter our confidence in the estimated treatment effect