Table 1 Participants Intervention Comparator Outcome Study design (PICOS) eligibility criteria for full-text assessment

Participants

Individuals with severe mental illness (SMI) ≥ 18 years.

Severe mental illness—bipolar affective disorder, schizophrenia, schizoaffective disorder, psychosis, any psychotic disorder.

Individuals with SMI under the age of 18 years.

Intervention

Pharmacy staff carrying out any of the following activities to any degree:

Screening/monitoring for cardiometabolic risk or metabolic syndrome, syndrome X or cardiometabolic disease or related diseases and any of the associated risk factors including lifestyle advice, diet, smoking, alcohol, exercise, cardiovascular disease, diabetes or prediabetes, HbA1c, glucose,weight, BMI, waist circumference, overweight, obesity, lipids, lipid abnormalities, blood pressure and hypertension.

Health promotion or risk reduction intervention for cardiometabolic risk or metabolic syndrome, syndrome X or cardiometabolic disease or related diseases or any of the associated risk factors.

Medicines management activities relating to the above.

Any of these activities carried out wholly by staff who are not pharmacy staff.

Activities that are carried out by pharmacy staff who are not listed.

Comparators (NB it is not compulsory to have a comparator for the study to be included)

Patients with SMI ≥ 18 years who did not receive any intervention.

Patients who do not have SMI who have any intervention.

Outcome

Primary outcome:

Change in rate of screening of cardiometabolic risk or metabolic syndrome, cardiometabolic diseases or syndrome X or any of the associated risk factors.

Change in health or lifestyle behaviour (risk reduction or health promotion).

Diagnosis of metabolic syndrome or identification of individual at high risk of metabolic syndrome.

Diagnosis of diseases related to cardiometabolic risk metabolic syndrome including diabetes, cardiovascular disease, hypertension, obesity, overweight, diabetes/high risk of diabetes/pre-diabetes.

Change in patient or physical health parameter e.g. BP outcome for the above.

Views, perception, opinions, experiences of service users, carers or any care professionals on the role of pharmacy to deliver ANY of the interventions.

Studies that do not measure the primary outcomes.

Study design

Any study design.

Any country.

Papers written in English only.

No study design will be excluded.

Papers not written in the English language.