Fig. 5

Effect of a animal models’ characteristics, b type of fractured bone, c time of collection healing bones, d type of NSAID, and e age of the animals on biomechanical bending measurements (maximum force to fracture) (MF) after administration of NSAID compared to the administration of a control vehicle. The columns indicate the effect estimate with the 95% confidence interval of the subgroups. SMD, standard mean difference–Hedges’ g mean. NM, not mentioned; NS-COX, non-selective cyclooxygenase inhibitor; COX2, selective-cyclooxygenase2 inhibitor