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Table 3 Recommendations for conducting a living systematic review, by stage of the review life cycle

From: How to update a living systematic review and keep it alive during a pandemic: a practical guide

Establishing a living systematic review

• Initiate a living systematic review only when the topic is a priority for decision-making and the evidence is uncertain and/or is changing quickly

• Estimate the time needed to conduct and update the living systematic review realistically

• Anticipate increasing numbers of records to screen with successive updates

Publishing a protocol

• Publish and register a protocol before starting the living systematic review

• Explicitly state the conditions for ending the living systematic review

• Document changes in a new protocol version before starting the next update

Setting up and managing the review team

• The team should have appropriate subject area and methodological and technical expertise

• Consider crowdsourcing volunteers to help with time-intensive tasks that require less content expertise

Study identification

• Automate searches, e.g. by using statistical software and application programme interface (APIs) to communicate with online database aggregators

• Store and manage identified records in a secure, online electronic database

Study selection and data collection

• Use software tools (e.g. Covidence, REDCap surveys) to organise and facilitate screening records

• Combine screening of titles and abstracts and full texts into one step

• Use text classifiers to automatically exclude ineligible articles, if appropriate

Data synthesis

• Synthesise the data using statistical software that can connect to an electronic database

• Create reproducible documents, tables, and/or figures to quickly update results when new studies are included

• Consider statistical issues associated with multiple updates

Publishing the results

• Publish updates first as preprints and then as open-access, peer-reviewed publications

• Choose an appropriate platform (i.e. journal, preprint server, or website) that makes the version of the review clear

• Consider a living systematic review website for sharing updates

Ending a living systematic review

• Decide on and state criteria for ending the living systematic review in the review protocol