Table 1 PubMed search strategy

(“chronic obstructive lung disease”[tiab] OR “chronic obstructive lung diseases”[tiab] OR “chronic airflow obstruction”[tiab] OR “chronic airflow obstructions”[tiab] OR “chronic airway obstruction”[tiab] OR “chronic airway obstructions”[tiab] OR “chronic obstructive lung disorder”[tiab] OR “chronic obstructive lung disorders”[tiab] OR “chronic obstructive pulmonary disease”[tiab] OR “chronic obstructive pulmonary diseases”[tiab] OR “chronic obstructive pulmonary disorder”[tiab] OR “chronic obstructive pulmonary disorders”[tiab] OR copd[tiab] OR coad[tiab] OR cobd[tiab] OR cold[tiab] OR emphysema[tiab] OR “Pulmonary Disease, Chronic Obstructive”[mh])

AND

(adherence[tiab] OR adherent[tiab] OR adhere[tiab] OR nonadherence[tiab] OR non-adherence[tiab] OR nonadherent[tiab] OR non-adherent[tiab] OR compliance[tiab] OR “patient compliance”[mh] OR medication adherence[mh] OR compliant[tiab] OR comply[tiab] OR noncompliance[tiab] OR non-compliance[tiab] OR noncompliant[tiab] OR non-compliant[tiab] OR “patient compliance”[mh])

AND

(((cohort[all] OR (control[all] AND study[all]) OR (control[tw] AND group*[tw]) OR epidemiologic studies[mh] OR program[tw] OR clinical trial[pt] OR comparative stud*[all] OR evaluation studies[all] OR statistics as topic[mh] OR survey*[tw] OR follow-up*[all] OR time factors[all] OR ci[tw]) NOT ((animals[mh:noexp] NOT humans[mh:noexp]) OR comment[pt] OR editorial[pt] OR review[pt] OR meta analysis[pt] OR case report[tw] OR consensus[mh] OR guideline[pt] OR history[sh]))

OR

(“Randomized controlled trial”[pt] OR “controlled clinical trial”[pt] OR random* [tiab] OR “clinical trials as topic”[mh:noexp] OR trial[ti] NOT ((animals[mh:noexp] NOT humans[mh:noexp]) OR comment[pt] OR editorial[pt] OR review[pt] OR meta analysis[pt] OR case report[tw] OR consensus[mh] OR guideline[pt] OR history[sh])))