Table 1 Main characteristics of included trials

Petersen et al. (2002) [31]

Denmark

Type 2 diabetes

62.8

20/22

4

56

TC, TG, HDL-c, LDL-c

TG changed significantly

Qin et al. (2015) [38]

China

NAFLD

45.15

36/34

4

90

TC, TG, HDL-c, LDL-c

TC and TG changed significantly

Bowden et al. (2009) [35]

USA

Dialysis

60

44/43

2

180

TC, TG, HDL-c, LDL-c

HDL-c and LDL-c changed significantly

Parviz Khajehdehi (2000) [36]

Iran

Dialysis

33.15

15/15

4.5

60

TC, TG, HDL-c, LDL-c

TG and LDL-c changed significantly

Wang et al. (2017) [32]

China

Type 2 diabetes

65.4

49/50

4

180

TC, TG, HDL-c, LDL-c

TG and HDL-c changed significantly

Bitzur et al. (2010) [26]

Israel

Hyperlipidemia

49.6

34/33

4

84

TC, TG, HDL-c, LDL-c

TG changed significantly

Pedersen et al. (2003) [33]

Denmark

Type 2 diabetes

63

23/21

4

56

TC, TG, HDL-c

TG and HDL-c changed significantly

Nilsen et al. (2001) [37]

Norway

MI

64

123/123

4

180

TC, TG, HDL-c

TC, TG, HDL-c changed significantly

Chan et al. (2003) [27]

Australia

Dyslipidemic

54.5

12/12

4

42

TC, TG, HDL-c, LDL-c

TG changed significantly

Schmidt et al. (2012) [28]

Germany

Dyslipidemic

41

9/8

3.05

84

TC, TG, HDL-c, LDL-c

TG and HDL-c changed significantly

Ramprasath et al. (2013) [25]

Canada

Healthy

28.23

8/8

3

28

TC, TG, HDL-c, LDL-c

Not changed significantly

Lee et al. (2014) [34]

USA

Type 2 diabetes

58

16/21

NR

56

TC, TG, HDL-c, LDL-c

TG and HDL-c changed significantly

Borthwick et al. (1998) [29]

England

Hyperlipidemia

53.4

29/26

4

84

TC, HDL-c

TG changed significantly

Thusgaard et al. (2009) [40]

Denmark

HIV

45

25/23

3.6

84

TC, TG, HDL-c, LDL-c

TG changed significantly

Yang et al. (2019) [39]

China

Hypertensive

56.7

35/34

4

84

TC, TG, HDL-c, LDL-c

Not changed significantly

Gidding et al. (2014) [30]

USA

Hyperlipidemia

14.1

19/18

4

56

TC, TG, HDL-c, LDL-c

LDL-c changed significantly