Characteristic | Studies |
---|---|
N = 132 | |
n (%) | |
Limitations related to study design | |
 Reported | 93 (70) |
  High RoB | 61 (48) |
  Heterogeneity | 70 (56) |
  Population | 50 (40) |
  Intervention | 15 (12) |
  Outcome | 11 (9) |
  Publication bias | 6 (5) |
  Small study effects | 5 (4) |
 Not reported | 39 (30) |
Concerns regarding the synthesis of OSs with RCTs | |
 Reported | 32 (24) |
  Risk of bias | 13 (10) |
  Inclusion of OSs and their interpretation | 9 (7) |
  Small number of available RCTs | 7 (5) |
  Risk of confounding | 4 (3) |
  Extraction of effect estimate | 2 (2) |
  Just caution on interpretation | 5 (4) |
 Not reported | 100 (81) |